Elective SET avoids twinning without decreasing delivery rate
MedWire News: Single embryo transfer (SET) avoids twin pregnancies without decreasing delivery rates, show the results of a French study on women aged under 36 years undergoing IVF or intracytoplasmic sperm injection.
The team investigated obstetric and neonatal outcomes among 53 women who underwent elective SET, and 98 women who chose double embryo transfer (DET).
Clinical pregnancy rates were similar in both the SET and DET groups, at 49.1 and 51.0 percent, and similar numbers of live deliveries also occurred, at 41.5 and 41.8 percent, respectively.
The twin delivery rate was significantly higher in the DET than the SET group, at 37.5 versus 3.5 percent, and neonatal outcomes were poorer among twins than singletons including having a higher risk for neonatal intensive care unit admission, and a low gestational age.
Specifically, mean gestational age was significantly higher in the SET group than in the DET twin group, at 36.7 versus 34.3 weeks, and the same was noted for mean birth weight, at 3031 versus 2367 g.
"Our results clearly highlight that the strategy to transfer a single fresh embryo achieves a cumulative rate of deliveries that is not lower than the cumulative rate after transfer of two fresh embryos," conclude Patricia Fauque, from Cochin-Port-Royal Hospital in Paris, and colleagues.
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By Sarah Guy