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23-05-2010 | Gynaecology | Article

Birth rates after frozen blastocyst transfer do not differ by race

Abstract

Free abstract

MedWire News: Live birth rates do not differ among African-American and white women undergoing IVF with frozen-thawed blastocysts, say US researchers.

Previous research has shown significantly lower live birth rates among African-American women undergoing fresh IVF cycles compared with white women. This is thought to be explained by uterine factors, including the presence of leiomyoma, write researcher Alicia Armstrong (National Institutes of Health, Bethesda, Maryland) and colleagues.

The current study finding was made despite the four-fold higher incidence of leiomyomas in African-American women.

The team compared pregnancy and live birth rates in a cohort of 50 African-American and 119 white women.

Overall outcomes were not significantly different for African-American women and white women, with clinical pregnancy rates of 42.0 and 39.5 percent, and live birth rates of 28.0 and 30.2 percent, respectively.

In total, 40 percent of African-American women had ultrasound-detected leiomyomas, compared with 10 percent of white women.

Even after exclusion of women with leiomyomas, the live birth rate did not differ significantly between races, at 23.3 percent compared with 31.5 percent, respectively.

Armstrong and colleagues conclude: “These data suggest that the ethnic disparity observed in fresh nondonor stimulated IVF cycles may result from causes other than leiomyomas.”

MedWire (www.medwire-news.md) is an independent clinical news service provided by Current Medicine Group, a trading division of Springer Healthcare Limited. © Springer Healthcare Ltd; 2010

By Sarah Guy