Endocrinology and metabolism

In a statement published in JAMA, the US Preventive Services Task Force upholds its 1996 recommendation against screening for thyroid cancer among asymptomatic adults.

Metabolic syndrome increases the risk for cardiovascular events in patients with chronic hepatitis B virus infection, study findings indicate.

Elevated levels of free thyroxine are associated with an increased risk of developing cancer.

Individuals with nonfunctional adrenal tumours (NFATs) have a nearly twofold increased risk of incident diabetes relative to those without adrenal tumours, shows research published in the Annals of Internal Medicine.

Pioglitazone may halt the progression of nonalcoholic steatohepatitis in patients with prediabetes or Type 2 diabetes, a randomised trial shows.

Researchers have discovered how a common variant of the melatonin receptor 1b burdens carriers with an increased risk of developing Type 2 diabetes.

A randomised trial published in Cell Metabolism demonstrates the “profound therapeutic effects” achievable by obese people who lose just 5% of their bodyweight.

Restricting use of an artificial pancreas to the evening and nighttime, with standard pump therapy the rest of the time, seems to deliver similar benefits to using one all day and night in patients with Type 1 diabetes, a study suggests.

Study findings indicate that oral treatments could offer a simpler alternative to upfront insulin for patients who have severe hyperglycaemia at the time of diagnosis with Type 2 diabetes.

A large registry analysis shows that younger people may be missing out on a general decline in mortality rates among patients with diabetes.

Sedentary, overweight adults with Type 2 diabetes can improve their cardiometabolic profile by engaging in very brief but regular periods of light walking or resistance exercise, research suggests.

Research shows that using a glucagon-like peptide-1 receptor agonist instead of a rapid-acting insulin analogue at mealtimes can reduce glycaemic variability in high-risk patients with Type 2 diabetes.

medwireNews: Parathyroid hormone (PTH) levels may be elevated by use of some antihypertensive agents but reduced by others, analysis of the Multi-Ethnic Study of Atherosclerosis (MESA) suggests. The ...

Body mass index is an inaccurate measure of obesity in older people, show data from NHANES.

Paediatric patients with triiodothyronine-predominant Graves' disease develop severe disease that needs increased doses of antithyroid drugs, a study shows.

Researchers report a dose–response relationship between body mass index and cardiovascular risk even in severely obese adolescents, making its assessment important to limit further disease progression.

Children with short stature benefit from receiving combined treatment with growth hormone and insulin-like growth factor-1, if they have low endogenous levels of the latter, a study shows.

Many children who require insulin treatment on diagnosis with Type 2 diabetes can be weaned off the medication, show findings from the run-in phase of the Treatment Options for Type 2 Diabetes in Adolescents and Youth study.

About three-quarters of cases of central precocious puberty in boys have no identifiable cause, say researchers.

Spontaneous catch-up growth after birth in short children who were born small for gestational age is a negative predictor of their long-term response to growth hormone treatment, say researchers.