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02-05-2011 | Diabetes | Article

Quitting smoking significantly reduces microalbuminuria in Type 2 diabetics


Free abstract

MedWire News: Study findings suggest that quitting smoking significantly reduces symptoms of microalbuminuria within 1 year in patients with newly diagnosed Type 2 diabetes.

The research also showed that smoking cessation was associated with noticeable improvements in metabolic health and blood pressure in these individuals.

Christina Voulgari (Athens University Medical School, Greece) and colleagues recruited 193 smokers with newly diagnosed Type 2 diabetes and microalbuminuria, aged an average of 56.4 years, to assess the impact of 1 year of smoking abstinence on various health parameters including blood pressure, microalbuminuric status, and glycemic control.

Of the participants, 120 managed to quit smoking for 1 year, while 73 continued to smoke.

The rate/prevalence of microalbuminuria, defined as having an albumin-to-creatinine ratio of 30.0-299.9 µg/mg creatinine, was reduced significantly more, to 22.5%, in the patients who stopped smoking, compared with 72.6% in those who continued smoking.

Although the reduction in microalbuminuria was the most significant effect of smoking cessation, smaller but still significant improvements occurred including better glycemic control, reduced blood pressure, and a reduction in dyslipidemia and insulin resistance in those who stopped smoking compared with those who continued.

Similarly, the prevalences of peripheral vascular disease and neuropathy were significantly reduced only in those men and women who stopped smoking.

"Although extended follow-up would be necessary to estimate the relationship between smoking cessation and amelioration of future microvascular as well as macrovascular disease events, our results underline the importance of an early smoking cessation education upon diagnosis of diabetes to possibly decrease the rate of the clinical and economical burden of diabetic complications," write the authors in the journal Metabolism: Clinical and Experimental.

"Health keepers should therefore consider giving this therapeutic intervention a higher priority," they conclude.

MedWire ( is an independent clinical news service provided by Springer Healthcare Limited. © Springer Healthcare Ltd; 2011

By Helen Albert

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