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31-10-2011 | Diabetes | Article

Hip circumference, height predict diabetes risk in women

Abstract

Free abstract

Medwire News: Height and hip circumference are each inversely associated with incident diabetes among women, report researchers.

These measurements can be used to provide additional insights into the effects of waist circumference on diabetes risk, they say.

"The separate independent associations of hip circumference and height with diabetes, have, in general, been investigated in White populations with conflicting results," write Farzad Hadaegh (Shahid Beheshti University, Tehran, Iran) and team.

"To the best of our knowledge, our study was the first to be conducted in a Middle East population that directly evaluated the predictive power of height and hip circumference in multivariate-adjusted models for incident diabetes separately in men and women," they say.

As reported in the journal Diabetic Medicine, the researchers followed-up 1589 men and 2132 women participants of the Tehran Lipid and Glucose Study for an average of 6 years and evaluated the effects of baseline anthropometric measures on incident diabetes.

Cox proportional hazard modeling revealed that height conferred no significant risk for diabetes in either men or women.

In contrast, each 1-standard deviation (SD) increment in age-adjusted hip circumference was associated with a 57% and 39% increase in risk for diabetes in men and women, respectively.

However, after further adjustment for waist circumference, this value was no longer significant in men (HR=0.87).

In women, both height and hip circumference had inverse associations with diabetes, at HRs of 0.69 and 0.76, respectively, for each 1-SD age-adjusted increment.

Furthermore, the HR for the relationship between waist circumference and incident diabetes in women increased by a further 7% and 54% with the inclusion of height and hip circumference, respectively.

"Had the negative confounding effects of the height and hip circumference not been considered, the contribution of waist circumference to incident diabetes would have been underestimated," say Hadaegh and team.

"While waist circumference can capture most of the relevant variation in risk for incident diabetes, the collection of information on height and hip circumference might still provide additional insights among women," they conclude.

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By Sally Robertson