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UK auxological referral criteria have low sensitivity for pathological short stature
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Combined pituitary hormone deficiency diagnosis often delayed
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Most young transgender people continue to identify as gender variant into adulthood
Mortality risk remains elevated even after Cushing’s syndrome remission
Findings from two studies highlight that mortality rates are elevated among patients with Cushing’s syndrome compared with healthy individuals, and this increased risk is attenuated, but still significant, in those who have achieved remission.
LINC 4 trial supports osilodrostat for the treatment of Cushing’s disease
Treatment with the 11β-hydroxylase inhibitor osilodrostat normalizes cortisol levels in the majority of patients with Cushing’s disease, report Mônica Gadelha and co-investigators from the LINC 4 trial.