STEMI risk eight times higher among younger smokers
medwireNews: Smoking is associated with an eightfold increase in the risk of ST-segment elevation myocardial infarction (STEMI) among people younger than 50 years of age, researchers report.
In an analysis of hospital admission and demographic data, Ever Grech (Northern General Hospital, Sheffield, UK) and colleagues found that the incidence of acute STEMI requiring percutaneous coronary intervention among smokers aged under 50, 50–65, and over 65 years was 59.7, 316.9, and 331.0 per 100,000 patient–years, respectively. The corresponding incidence rates among ex- and never smokers were 7.0, 60.9, and 106.8 per 100,000 patient–years.
These incidence rates translate into an 8.47-fold increase in the risk of STEMI among smokers under the age of 50 compared with nonsmokers in the same age group. The risk was increased 5.20-fold in smokers aged 50–65 years, and 3.10-fold among smokers aged over 65 years.
These findings show that smoking is a “major risk factor for young patients with STEMI,” writes Yaron Arbel (Tel Aviv Medical Center, Israel) in an editorial accompanying the research published in Heart. He notes that despite medical advances in recent years, “the short-term and long-term risks for mortality have not diminished in smokers compared with non-smokers.”
The commentator recommends that “medical, legislative, commercial and educational efforts” are required to reduce smoking-related risks, especially among young people, and that initiatives should focus on prevention, education, and treatment.
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