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25-02-2010 | Bone health | Article

Midlife lifestyle factors predict male hip fracture in later life


Free abstract

MedWire News: The risk for hip fracture in men is predicted by lifestyle, occupational, and health factors, reveals research published in the journal Osteoporosis International.

The study examined midlife factors that would predict hip fracture in 7495 men aged 46–56 years old who were living in Gothenburg, Sweden, between 1970 and 1973 and who were followed-up for over 30 years.

The participants completed questionnaires on lifestyle, psychological stress, occupational class, and history of diabetes, myocardial infarction, and stroke. Alcoholism was assessed using register data and Swedish hospital data were examined for diagnoses of stroke, dementia, and first hip fracture.

Overall, 6% of men suffered hip fracture during follow-up, report Pinelopi Trimpou (University of Gothenburg, Sweden) and co-workers.

Multivariate analysis showed that hip fracture was significantly and independently associated with age at baseline, greater height, low occupational class, tobacco smoking, alcohol abuse, and stroke, or dementia during follow-up. The strongest risk factors were alcohol abuse, stroke, and dementia, all of which are known to be associated with an increased risk for falls, the researchers note.

In contrast, the risk for hip fracture decreased with increasing leisure time spent in physical activity (but not physical activity at work), body mass index, and coffee consumption.

“Lifestyle modifications that promote physical activity and nonsmoking could potentially prevent a significant proportion of hip fractures in men,” Trimpou et al conclude.

“The association between low occupational class and hip fracture may reflect nutritional factors, which need to be better identified.”

MedWire ( is an independent clinical news service provided by Current Medicine Group, a trading division of Springer Healthcare Limited. © Springer Healthcare Ltd; 2010

By Lynda Williams

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