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Asthma

Asthma

06-09-2018 | Asthma | News | Article

Single blood eosinophil measure predicts eosinophilic asthma

A single blood eosinophil count could predict persistent eosinophilia in patients with adult-onset asthma, study findings show.

03-09-2018 | Asthma | News | Article

Proportion of asthma patients who could benefit from anti-IL-5 treatment estimated

Researchers estimate that 2% of patients with adult-onset eosinophilic asthma could benefit from treatment involving antibodies against the interleukin-5 pathway.

24-07-2018 | Asthma | News | Article

Proportion of asthma patients who could benefit from anti-IL-5 treatment estimated

Researchers estimate that 2% of patients with adult-onset eosinophilic asthma could benefit from treatment involving antibodies against the interleukin-5 pathway.

04-07-2018 | Asthma | News | Article

Asthma risk prediction score accounts for early treatment response

Researchers have developed a measure for predicting future asthma risk based on patient characteristics and current level of asthma control.

20-06-2018 | Asthma | News | Article

Good prognosis for patients with mild asthma

Research findings can reassure patients with mild asthma that the long-term prognosis is good, with only a tenth of patients transitioning to more severe disease over 10 years.

08-05-2018 | Asthma | News | Article

Eosinophilia linked to lung function decline irrespective of asthma symptoms

High blood eosinophil counts are associated with airflow obstruction and lung function decline in patients with asthma, but also in people without respiratory symptoms, population-based study findings show.

12-03-2018 | Asthma | News | Article

Exacerbation frequency linked to lung function decline in severe eosinophilic asthma

Repeated exacerbations in patients with severe eosinophilic asthma may be associated with accelerated deterioration of lung function, study findings show.

13-02-2018 | Asthma | News | Article

Initiation criteria for mepolizumab sufficient for determining long-term benefit

Researchers have been unable to find a reliable rule for identifying patients who are likely to benefit from continued long-term mepolizumab treatment for severe eosinophilic asthma.

16-01-2018 | Asthma | News | Article

Allergic airway inflammation stimulates a dynamic ILC2 phenotype

Researchers have found that the group 2 innate lymphoid cell phenotype is more heterogeneous than previously thought, with a surface marker and gene expression profile that is highly dynamic.

18-12-2017 | Asthma | News | Article

Increasing physical activity could aid severe asthma management

Researchers recommend addressing inactivity and sedentary time as a possible nonpharmacologic approach to managing severe asthma.

04-10-2017 | Asthma | News | Article

B cells have key role in Th-mediated allergic response

Results of a study conducted in mouse models of allergy suggest that B cells have an important role in propagating T-helper cell-mediated responses to house dust mites.

04-10-2017 | Asthma | News | Article

Sex, obesity, and immune disturbances inform severe asthma phenotype in later life

With advancing age, asthma becomes more prevalent in women than men and is associated with obesity, greater airflow limitation, and lower markers of T-helper cell type 2 inflammation, study findings show.

04-10-2017 | Asthma | News | Article

Blood eosinophils vary over time in relation to exacerbation and asthma control

Analysis of the COBRA cohort of adult patients with asthma provides insights into the role eosinophil count plays as a biomarker for predicting exacerbations and treatment efficacy.

04-09-2017 | Asthma | News | Article

Japanese subphenotypes of type 2 severe asthma identified

The majority of Japanese patients with severe, difficult-to-treat asthma are likely to present with type 2 asthma and a substantial proportion overlap between two or more subphenotypes, a study suggests.

04-09-2017 | Asthma | News | Article

Gene profiles differ in adult- and childhood-onset severe asthma

A European study suggests gene profiles differ in severe asthma that begins in adulthood rather than childhood, indicating distinct underlying mechanisms at work.

04-09-2017 | Asthma | News | Article

Global decline in asthma deaths may have stalled

Death rates from asthma among younger people appear to have plateaued in the past decade despite substantial improvements before this, a study in The Lancet suggests.

09-08-2017 | Asthma | News | Article

Point-of-care device shows promise for blood eosinophil count in severe asthma

Study findings validate a point-of-care device for assessing blood eosinophils that could help in the management of severe asthma.

09-08-2017 | Asthma | News | Article

Asthma phenotypes change with age

Researchers have found that older patients with asthma have different phenotypes to those of younger patients.

09-08-2017 | Asthma | News | Article

Obesity impacts eosinophilia biomarker sensitivity

Markers of inflammation conventionally used to identify eosinophilic airway inflammation in patients with asthma may not be effective in obese individuals, research suggests.

17-07-2017 | Asthma | News | Article

QoL measure gives the asthma patient’s perspective

Researchers have devised a new measure for assessing the effect of asthma on quality of life from the patient’s perspective.

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