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04-05-2020 | Rheumatology | News | Article

COVID-19 outcomes described in patients with large-vessel vasculitis

Researchers outline the impact of COVID-19 in a cohort of Italian patients with large-vessel vasculitis.

04-05-2020 | Rheumatology | News | Article

​​​​​​​Biologic, JAK inhibitor use may not be linked to worse COVID-19 outcomes

The authors of a prospective US case series outline the experience of 86 patients with immune-mediated inflammatory diseases and confirmed or highly suspected COVID-19.

01-05-2020 | Rheumatology | News | Article

CloroCovid-19 results reinforce the need for caution with chloroquine, hydroxychloroquine use

Findings from the phase 2b CloroCovid-19 trial indicate that patients with severe suspected COVID-19 who are treated with high-dose chloroquine have higher rates of death than those given low-dose chloroquine.

01-05-2020 | Rheumatology | News | Article

Disease characteristics predict belimumab response in SLE

High disease activity, short disease duration, and low baseline damage are associated with an increased response to belimumab in patients with systemic lupus erythematosus, real world study data show.

30-04-2020 | Rheumatology | News | Article

Early rheumatologist attention delivers improved RA remission rates

People with rheumatoid arthritis who visit a rheumatologist within the first 6 weeks of experiencing symptoms are more likely to achieve sustained DMARD-free remission than those who wait for 7–12 weeks, suggest observational study results.

30-04-2020 | Rheumatology | News | Article

EULAR provides guidance on managing immunotherapy-related rheumatic irAEs

EULAR has issued recommendations on the management of rheumatic immune-related adverse events in people with cancer treated with immune checkpoint inhibitors.

29-04-2020 | Rheumatology | News | Article

RA disease activity markers identify patients at risk for worsening ventricular function

The risk for impaired left ventricular systolic function is significantly increased in patients with rheumatoid arthritis if they are positive for anticitrullinated peptide antibody, have high disease activity, and a long duration of disease, study findings suggest.

29-04-2020 | Rheumatology | News | Article

Hydroxychloroquine ‘does not seem to prevent COVID-19’ in people with lupus

The authors of a French case series report the clinical experiences of 17 patients with systemic lupus erythematosus undergoing long-term treatment with hydroxychloroquine who developed COVID-19.

28-04-2020 | Rheumatology | News | Article

Regular glucosamine supplementation may lower mortality risk

Findings from a large prospective cohort study show that regular use of a glucosamine supplement is associated with a reduced risk for all-cause and cause-specific mortality among the general population.

27-04-2020 | Rheumatology | News | Article

COVID-19: FDA warns against chloroquine, hydroxychloroquine use outside specific settings

The US FDA has issued a safety alert warning that chloroquine and hydroxychloroquine for COVID-19 should not be used outside of hospital settings or clinical trials due to an elevated risk for heart rhythm problems with the agents.

27-04-2020 | Rheumatology | News | Article

Phase 2 RA trials ‘systematically overestimate’ treatment efficacy

The reported efficacy of treatments for rheumatoid arthritis is consistently higher in phase 2 than phase 3 randomized controlled trials, mainly due to differences in inclusion criteria, say the authors of a systematic review and meta-analysis.

24-04-2020 | Rheumatology | News | Article

Rheumatologists, patients report healthcare changes during COVID-19 pandemic

Findings from two questionnaire studies suggest that a substantial proportion of rheumatology patients have experienced changes to their disease management since the emergence of COVID-19.

23-04-2020 | Rheumatology | News | Article

Infection-related hospitalizations on the rise among people with gout

The rate of serious infections requiring hospitalization, particularly sepsis, is increasing among people with gout, US longitudinal study data show.

23-04-2020 | Rheumatology | News | Article

COVID-19: Immune effects of rituximab require further investigation

A case report published in the Annals of the Rheumatic Diseases describes the experience of a rituximab-treated patient with ANCA-associated vasculitis who developed severe COVID-19.

22-04-2020 | Rheumatology | News | Article

Smoking identified as a risk factor for ANCA-associated vasculitis

Current and former cigarette smoking is strongly associated with an increased risk for antineutrophil cytoplasmic antibody-associated vasculitis, researchers report.

21-04-2020 | Rheumatology | News | Article

Zoledronic acid disappoints in ZAP2 knee osteoarthritis trial

Annual infusions of zoledronic acid do not reduce cartilage volume loss, pain, or bone marrow lesion size in people with knee osteoarthritis, suggest findings from the phase 3 ZAP2 trial.

20-04-2020 | Rheumatology | News | Article

First data from the COVID-19 Global Rheumatology Alliance released

The COVID-19 Global Rheumatology Alliance has released preliminary data on 110 individuals with rheumatic disease and comorbid COVID-19.

20-04-2020 | Rheumatology | News | Article

Dapansutrile ‘has substantial potential’ for treating gout flares

Findings from a proof-of-concept phase 2a trial provide preliminary evidence to suggest that dapansutrile, an inhibitor of the NLRP3 inflammasome, may be a promising therapeutic option for gout flares.

17-04-2020 | Rheumatology | News | Article

‘Dearth of evidence’ to support prophylactic chloroquine, hydroxychloroquine use for COVID-19

Findings from a systematic review published in the International Journal of Rheumatic Diseases confirm that there is currently insufficient evidence to support the efficacy of chloroquine or hydroxychloroquine for the prevention of COVID-19.

16-04-2020 | Rheumatology | News | Article

​​​​​​​ACR issues guidance on COVID-19 and rheumatology care

The American College of Rheumatology has issued clinical guidance for the care of people with rheumatic diseases in the context of the COVID-19 pandemic.

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