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Rheumatology

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26-10-2020 | Rheumatology | News | Article

Telemedicine ‘can reasonably be offered’ as part of usual rheumatoid arthritis care

The authors of an observational study report “few differences” in quality of care and patient-reported outcomes among people with rheumatoid arthritis who took part in telemedicine consultations compared with those attending in-person appointments only.

22-10-2020 | Rheumatology | News | Article

Early RCT evidence suggests tocilizumab may not be beneficial for COVID-19

Findings from three randomized controlled trials suggest that treatment with the IL-6 inhibitor tocilizumab has little benefit for hospitalized patients with COVID-19.

22-10-2020 | Rheumatology | News | Article

Support for further investigation of otilimab in rheumatoid arthritis

Otilimab, a human monoclonal antibody that inhibits GM-CSF, may warrant further investigation for the treatment of rheumatoid arthritis, indicate findings from two phase 2 trials published in The Lancet Rheumatology.

21-10-2020 | Rheumatology | News | Article

COVID-19 lockdown had ‘immediate negative consequences’ for rheumatology patients

Over half of a UK cohort of rheumatology patients experienced worsening in musculoskeletal symptoms during the COVID-19 lockdown period, say researchers.

20-10-2020 | Rheumatology | News | Article

Outpatient rehabilitation no better than home exercise for TKA recovery

Outpatient therapist-led rehabilitation offers no clinical benefit over a home-based exercise regimen in patients with knee osteoarthritis at risk for poor outcomes after total knee arthroplasty, shows the TRIO trial.

19-10-2020 | Rheumatology | News | Article

Recommendations made for offsetting negative effects of COVID-19 on rheumatology practice

Better access to treatment and a dedicated telemedicine platform are among the suggestions made to remedy the negative impact the COVID-19 pandemic has had on rheumatology practice in Arab countries, following results from a recent survey.

16-10-2020 | Rheumatology | News | Article

Mood disorders linked to biologic initiation, switching in rheumatic diseases

Depression and anxiety are significantly associated with the introduction and switching of biologic DMARDs in patients with inflammatory rheumatic diseases, population-based study data show.

15-10-2020 | Rheumatology | News | Article

Baricitinib may warrant further investigation for COVID-19 pneumonia

Preliminary findings from an observational study suggest that add-on treatment with baricitinib may improve respiratory function in patients with moderate-to-severe SARS-CoV-2 pneumonia.

14-10-2020 | Rheumatology | News | Article

Latent tuberculosis infection rare among secukinumab users

Latent tuberculosis infection is uncommon among people receiving secukinumab for psoriasis, psoriatic arthritis, or ankylosing spondylitis, shows a pooled analysis of clinical trial data.

13-10-2020 | Rheumatology | News | Article

RECOVERY: Hydroxychloroquine does not prevent COVID-19 deaths

Treatment with hydroxychloroquine does not reduce 28-day mortality risk among patients hospitalized with COVID-19, show results from the large-scale UK-based RECOVERY trial.

12-10-2020 | Rheumatology | News | Article

Increased awareness for VTE needed in inflammatory diseases

People with immune-mediated inflammatory disease are almost 50% more likely to develop a venous thromboembolism than those without such conditions, UK study data show.

09-10-2020 | Rheumatology | News | Article

Early data show benefits of romilkimab in diffuse cutaneous SSc

Romilkimab could significantly improve skin fibrosis in people with early diffuse cutaneous systemic sclerosis, results of a phase 2 proof-of-concept study suggest.

08-10-2020 | Rheumatology | News | Article

Knee, hip osteoarthritis linked to increased risk for venous thromboembolism

Patients with osteoarthritis in the knee and hip, but not the hand, have an increased risk for venous thromboembolism, which may be exacerbated by knee and hip replacements, researchers report.

07-10-2020 | Rheumatology | News | Article

Inflammatory arthritis disease activity unaffected by reduced in-patient appointments

Fewer in-person interactions between inflammatory arthritis patients and their rheumatologists during the COVID-19 pandemic wave in Switzerland may have led to reduced drug adherence, but patients’ disease activity has remained stable, an analysis of patient-reported outcomes reveals.

06-10-2020 | Rheumatology | News | Article

Seletalisib may deserve further exploration in primary Sjögren’s syndrome

Treatment with the selective PI3K-delta inhibitor seletalisib may reduce disease activity in patients with moderate-to-severe primary Sjögren’s syndrome, suggest data from a phase 2 proof-of-concept study.

05-10-2020 | Rheumatology | News | Article

Placebo responses in RA trials are more than just a psychologic effect

The placebo response among patients with rheumatoid arthritis participating in clinical trials is not only a subjective phenomenon, it is also evident in biochemical data, study findings indicate.

02-10-2020 | Rheumatology | News | Article

Turmeric extract may reduce knee osteoarthritis pain

Treatment with Curcuma longa extract may reduce pain but not swelling among patients with symptomatic knee osteoarthritis and knee effusion–synovitis, Australian researchers report.

01-10-2020 | Rheumatology | News | Article

QoL benefits of stem cell transplantation shown in SSc

Autologous hematopoietic stem cell transplantation leads to early and sustained clinically relevant improvements in health-related quality of life among patients with systemic sclerosis, study findings indicate.

30-09-2020 | Rheumatology | News | Article

PATCH trial shows ‘no clinical benefit’ of hydroxychloroquine for COVID-19 prophylaxis

Prophylactic use of hydroxychloroquine does not reduce the risk for SARS-CoV-2 infection among hospital-based healthcare workers at high risk for exposure, suggest findings from a randomized controlled trial.

30-09-2020 | Rheumatology | News | Article

Hydroxychloroquine use may not lower COVID-19 risk in people with RMDs

Long-term hydroxychloroquine treatment is not associated with a reduced risk for developing COVID-19 among patients with rheumatic and musculoskeletal diseases, research suggests.

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