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Rheumatology

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21-04-2020 | Rheumatology | News | Article

Zoledronic acid disappoints in ZAP2 knee osteoarthritis trial

Annual infusions of zoledronic acid do not reduce cartilage volume loss, pain, or bone marrow lesion size in people with knee osteoarthritis, suggest findings from the phase 3 ZAP2 trial.

20-04-2020 | Rheumatology | News | Article

First data from the COVID-19 Global Rheumatology Alliance released

The COVID-19 Global Rheumatology Alliance has released preliminary data on 110 individuals with rheumatic disease and comorbid COVID-19.

20-04-2020 | Rheumatology | News | Article

Dapansutrile ‘has substantial potential’ for treating gout flares

Findings from a proof-of-concept phase 2a trial provide preliminary evidence to suggest that dapansutrile, an inhibitor of the NLRP3 inflammasome, may be a promising therapeutic option for gout flares.

17-04-2020 | Rheumatology | News | Article

‘Dearth of evidence’ to support prophylactic chloroquine, hydroxychloroquine use for COVID-19

Findings from a systematic review published in the International Journal of Rheumatic Diseases confirm that there is currently insufficient evidence to support the efficacy of chloroquine or hydroxychloroquine for the prevention of COVID-19.

16-04-2020 | Rheumatology | News | Article

​​​​​​​ACR issues guidance on COVID-19 and rheumatology care

The American College of Rheumatology has issued clinical guidance for the care of people with rheumatic diseases in the context of the COVID-19 pandemic.

16-04-2020 | Rheumatology | News | Article

SLE flares less likely in pregnancy if disease quiescent at conception

The risk for flares during and after pregnancy is low and the severity typically mild in women who have inactive or stable systemic lupus erythematosus in early pregnancy, show data from the PROMISSE study.

15-04-2020 | Rheumatology | News | Article

DMARD use not linked to postsurgical complications in people with RA

Individuals with rheumatoid arthritis are at no more risk for postsurgical complications if they have used a biologic or targeted synthetic DMARD in the weeks preceding surgery than if they had used methotrexate, US research shows.

14-04-2020 | Rheumatology | News | Article

Knee pain patterns key to understanding symptomatic osteoarthritis disease progression

Advanced knee pain patterns involving constant plus intermittent pain are associated with increased severity of pain and radiographic knee osteoarthritis duration and severity, suggest longitudinal study data.

09-04-2020 | Rheumatology | News | Article

Meta-analysis supports efficacy of denosumab for glucocorticoid-induced osteoporosis

Denosumab significantly increases bone mineral density in people with glucocorticoid-induced osteoporosis and may be more effective than bisphosphonates, show the results of a systematic review and meta-analysis.

09-04-2020 | Rheumatology | News | Article

​​​​​​​Support for physical therapy over glucocorticoid injections for knee osteoarthritis

People with symptomatic knee osteoarthritis who undergo physical therapy have greater reductions in pain and functional disability over 1 year than those given intra-articular glucocorticoid injections, randomized trial results suggest.

08-04-2020 | Rheumatology | News | Article

ACR advises on resource allocation during COVID-19 pandemic

The ACR has issued guiding principles for the allocation of hydroxychloroquine, IL-1 and 6 antagonists, JAK inhibitors, and eculizumab during the COVID-19 pandemic.

07-04-2020 | Rheumatology | News | Article

EULAR, ERA–EDTA issue guidelines for managing lupus nephritis

EULAR and the Renal Association–European Dialysis and Transplant Association have issued updated recommendations for the management of lupus nephritis.

06-04-2020 | Rheumatology | News | Article

Support for further study of leflunomide–hydroxychloroquine for primary Sjögren’s syndrome

Findings from RepurpSS-I, a small phase 2a trial, suggest that leflunomide–hydroxychloroquine combination therapy has a favorable safety profile and gives rise to a clinical response in patients with primary Sjögren’s syndrome.

03-04-2020 | Rheumatology | News | Article

Preliminary findings suggest no need for preventive DMARD withdrawal during COVID-19 pandemic

The first report of patients with rheumatic diseases and SARS-CoV2 infection in Italy suggests that people treated with biologic or targeted synthetic DMARDs may not be at increased risk for severe complications from COVID-19.

03-04-2020 | Rheumatology | News | Article

Mild COVID-19 reported in a patient with SSc–ILD

The authors of a case report discuss the experience of a patient with systemic sclerosis-associated interstitial lung disease who developed a mild form of COVID-19.

03-04-2020 | Rheumatology | News | Article

Rheumatologists urge caution on chloroquine, hydroxychloroquine use for COVID-19

Rheumatologists highlight that more research needs to be carried out before chloroquine and hydroxychloroquine can be recommended for the treatment of COVID-19, and emphasize the need for adequate supplies of these agents for people with rheumatic diseases.

02-04-2020 | Rheumatology | News | Article

Seasonal influenza vaccine recommended in patients with autoimmune rheumatic diseases

Immunocompromised patients with autoimmune rheumatic diseases who receive the influenza vaccine have a reduced risk for respiratory-related diseases, according to a longitudinal study published in Rheumatology.

01-04-2020 | Rheumatology | News | Article

EULAR launches COVID-19 database

EULAR has announced the launch of a European pediatric and adult registry to monitor the outcomes of patients with rheumatic and musculoskeletal diseases who develop COVID-19.

31-03-2020 | Rheumatology | News | Article

Support for combining non-methotrexate csDMARDs with biologics in RA patients

Non-methotrexate conventional synthetic csDMARDs may be “efficient alternatives” to methotrexate for using in combination with biologics for the treatment of rheumatoid arthritis, researchers report.

30-03-2020 | Rheumatology | News | Article

Secukinumab gets EU nod for nonradiographic axSpA

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