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16-08-2019 | Rheumatology | News | Article

Frailty linked to worsening function in RA patients

Frailty may be a risk factor for worsening physical function among people with rheumatoid arthritis, research suggests.

15-08-2019 | Rheumatology | News | Article

Preoperative opioid use linked to adverse outcomes after knee replacement

Among people with osteoarthritis or rheumatoid arthritis who undergo total knee replacement, continuous preoperative opioid use is associated with an increased risk for adverse outcomes, study findings suggest.

14-08-2019 | Rheumatology | News | Article

Support for switching between upadacitinib and adalimumab in RA patients

48-week results from the SELECT-COMPARE study indicate that upadacitinib has sustained efficacy in patients with rheumatoid arthritis, and that individuals with an inadequate response to upadacitinib or adalimumab may benefit from switching to the alternate therapy.

14-08-2019 | Rheumatology | News | Article

Vaccination may increase gout flare risk

The increased risk for gout flares following receipt of the aluminum-free recombinant zoster vaccine is not unique to this vaccine but is instead associated with vaccination in general, regardless of the adjuvant used, US researchers report.

13-08-2019 | Rheumatology | News | Article

OARSI guidelines for non-surgical management of osteoarthritis released

The Osteoarthritis Research Society International has issued updated evidence-based recommendations for the nonsurgical treatment of knee, hip, and polyarticular osteoarthritis.

12-08-2019 | Oncology | News | Article

Individuals with autoimmune disease ‘good candidates’ for cancer immunotherapy

A French database analysis lends further support for the use immune checkpoint inhibitors for cancer in patients with pre-existing autoimmune disease.

09-08-2019 | Rheumatology | News | Article

GCA no less common in Black than White individuals

The incidence of giant cell arteritis is similar among Black and White people, suggests an analysis of a cohort from a US tertiary care center.

08-08-2019 | Rheumatology | Highlight | Article

NSAIDs contribute ‘substantially’ to increased CVD risk in osteoarthritis

People with osteoarthritis have a significantly higher risk for developing cardiovascular disease than those without, and the use of nonsteroidal anti-inflammatory drugs mediates a considerable proportion of this association, researchers report.

07-08-2019 | Rheumatology | News | Article

Bariatric surgery may not reduce RA risk

Among people with obesity, undergoing bariatric surgery is not associated with a reduction in the risk for developing rheumatoid arthritis, researchers report.

06-08-2019 | Rheumatology | News | Article

Tropomyosin receptor kinase A inhibition shows potential for knee osteoarthritis

Findings from a phase II proof-of-concept trial suggest that the tropomyosin receptor kinase A inhibitor GZ389988A may provide pain relief for patients with knee osteoarthritis.

05-08-2019 | Rheumatology | News | Article

Real-world data support apremilast for Behçet’s disease

Findings from an Italian real-world study provide support for the phosphodiesterase-4 inhibitor apremilast as a treatment option for people with Behçet’s disease.

02-08-2019 | Rheumatology | News | Article

Machine learning shows promise for predicting TNF inhibitor response

A machine-learning model may help to predict which rheumatoid arthritis patients are likely to respond to treatment with TNF inhibitors, researchers report.

31-07-2019 | Rheumatology | News | Article

Predictors of successful biologic discontinuation in RA patients described

A systematic review has identified several factors predicting successful discontinuation of biologic DMARDs in people with rheumatoid arthritis, including low disease activity and good physical function.

30-07-2019 | Rheumatology | News | Article

Abatacept fails to improve skin disease in SSc trial

Findings from the phase II ASSET trial suggest that patients with diffuse cutaneous systemic sclerosis who are treated with abatacept do not experience significantly greater improvements in skin disease than those given placebo.

29-07-2019 | Rheumatology | News

FDA gives nod to adalimumab-bwwd

Click through for more information on the approval

29-07-2019 | Rheumatology | News | Article

FDA adds boxed warnings to tofacitinib label

Click through for further details on the new warnings

26-07-2019 | Rheumatology | News | Article

Asbestos, silica exposure linked to RA risk

Male workers with occupational exposure to asbestos or silica may have an elevated risk for developing rheumatoid arthritis, Swedish researchers report.

25-07-2019 | Rheumatology | News | Article

FINCH 2: Further evidence for filgotinib as a treatment option for RA

Rheumatoid arthritis (RA) patients with an inadequate response or intolerance to biologic DMARDs who are treated with the selective JAK1 inhibitor filgotinib are more likely to achieve a clinical response than those given placebo, phase III trial results suggest.

24-07-2019 | Rheumatology | News | Article

EULAR issues updated guidance for managing large vessel vasculitis

EULAR has released updated recommendations for the management of large vessel vasculitis, including giant cell arteritis and Takayasu arteritis.

24-07-2019 | Rheumatology | News | Article

Success of etanercept withdrawal linked to pre-withdrawal remission status

The likelihood of maintaining remission following etanercept withdrawal is highest among rheumatoid arthritis patients with the greatest degree of remission prior to the start of withdrawal and decreases with decreasing remission status, research shows.

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