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Rheumatology

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24-05-2022 | Rheumatology | News | Article

MIS-C clinical features largely unchanged since first COVID-19 wave

The incidence and clinical features of multisystem inflammatory syndrome in children were similar during the delta wave of COVID-19 to those observed during the first year of the pandemic among unvaccinated children and adolescents, Danish research suggests.

23-05-2022 | Rheumatology | News | Article

Polygenic risk scores for advanced osteoarthritis validated in older adults

Polygenic risk scores for advanced knee and hip osteoarthritis are significantly associated with the likelihood of requiring joint replacement in community-dwelling older adults, Australian study findings indicate.

20-05-2022 | Rheumatology | News | Article

EULAR issues guidance on telemedicine in rheumatology

EULAR has put forward “points to consider” that aim to guide the integration of telehealth into rheumatology clinical practice.

19-05-2022 | Rheumatology | News | Article

Residual disease burden highlighted in people with psoriatic arthritis

Some people with psoriatic arthritis continue to experience a range of residual symptoms despite meeting stringent treatment targets, indicates a systematic review of real-world data.

17-05-2022 | Rheumatology | News | Article

Vascular plaque burden could predict future CVD risk in people with SLE

The overall burden of vascular plaque measured on ultrasound scans is significantly associated with future risk for cardiovascular disease events in people with systemic lupus erythematosus, study findings indicate.

16-05-2022 | Rheumatology | News | Article

Familial autoimmunity may be linked to celiac disease risk in JIA

Individuals with juvenile idiopathic arthritis have a higher-than-average incidence of celiac disease that may be associated with a family history of autoimmunity and a more severe disease course, Italian researchers report.

12-05-2022 | Rheumatology | Highlight | Article

Study identifies risk factors for RMD flares following COVID-19 vaccination

Research from the COVID-19 Global Rheumatology Alliance has identified a number of factors, including diagnosis and vaccine type, that are associated with flare risk following vaccination among people with rheumatic and musculoskeletal diseases.

12-05-2022 | Rheumatology | News | Article

Seroconversion, prior infection may reduce breakthrough COVID-19 risk in people with IMIDs

People on immunomodulatory therapy have similar rates of breakthrough SARS-CoV-2 infection to healthy controls, with a reduced risk seen in those with prior infection or seroconversion after vaccination, research suggests.

12-05-2022 | Rheumatology | News | Article

Neutrophils may be a biomarker for SSc progression, mortality risk

Study findings suggest that higher blood neutrophil counts and neutrophil-to-lymphocyte ratio are associated with an increased risk for disease progression and mortality in patients with early systemic sclerosis.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

11-05-2022 | Rheumatology | News | Article

Type, intensity of immunomodulatory therapy ‘of major relevance’ for COVID-19 vaccine response

Findings from two studies suggest that the type of immunomodulatory therapy, and whether agents are used as monotherapy or in combination, may impact how well patients with immune-mediated diseases respond to COVID-19 vaccines.

10-05-2022 | Rheumatology | News | Article

CLUES study highlights racial disparities in end-organ lupus manifestations

Hispanic and Asian people with systemic lupus erythematosus are at significantly greater risk for developing renal, hematologic, and multiorgan disease than their White counterparts, US study findings indicate.

09-05-2022 | Rheumatology | News | Article

Psoriasis may impact clinical course of peripheral spondyloarthritis

Among people with peripheral spondyloarthritis, those who also have psoriasis show different clinical characteristics to those without the skin condition, study findings indicate.

06-05-2022 | Rheumatology | News | Article

Adding BTK inhibitor to upadacitinib offers no benefit in RA

Treatment with a fixed-dose combination of the novel BTK inhibitor elsubrutinib and the JAK inhibitor upadacitinib offers no additional benefit over upadacitinib alone for people with rheumatoid arthritis, suggest phase 2 trial results.

05-05-2022 | Rheumatology | News | Article

Support for gout self-management for improving urate levels

Supported self-management improves attainment of urate targets in people with gout, research suggests.

04-05-2022 | Rheumatology | News | Article

Colchicine prophylaxis associated with ‘markedly reduced’ gout flare risk after COVID-19 vaccination

COVID-19 vaccination with inactivated virus vaccines is associated with an increased risk for flares among men with gout, and colchicine prophylaxis may help reduce this risk, researchers report.

03-05-2022 | Rheumatology | News | Article

Data do not support targeted DMARDs for dementia risk reduction

Treatment with DMARDs that target cytokine signaling is not associated with a reduced risk for Alzheimer’s disease and related dementia in people with rheumatoid arthritis, US researchers report.

29-04-2022 | Rheumatology | News | Article

IL-22 levels may guide PsA treatment selection

Measuring IL-22 levels may help predict whether IL-17 inhibitors or TNF inhibitors are more suitable for patients with psoriatic arthritis, Japanese research suggests.

28-04-2022 | Rheumatology | News | Article

Semi-automated hip OA classification based on DXA images has potential to predict clinical outcomes

A semi-automated method of classifying hip osteoarthritis into grades based on DXA images may be able to predict the need for total hip replacement, suggests research presented at the British Society for Rheumatology 2022 Annual Conference in Glasgow, UK.

27-04-2022 | Rheumatology | News | Article

SLE tied to adverse stroke outcomes in women

Women with systemic lupus erythematosus are more likely to experience adverse outcomes following stroke than those without, research suggests.

26-04-2022 | Rheumatology | News | Article

COVID-19: Support for pausing rituximab, considering other treatments in people with RA

Study findings presented at the British Society for Rheumatology 2022 Annual Conference in Glasgow, UK, provide support for pausing or delaying rituximab and considering other treatment options for people with rheumatoid arthritis during the COVID-19 pandemic.