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16-08-2018 | Rheumatology | Highlight | Article

Editor's pick

TNF inhibitors unlikely to raise cancer recurrence risk in RA patients

Treatment with tumour necrosis factor inhibitors is not associated with a significantly increased risk of recurrent cancer among patients with rheumatoid arthritis, researchers report.


Ann Intern Med 2018; doi:10.7326/M17-2812

16-08-2018 | Rheumatology | News | Article

Predictors of remission in RA patients identified

Two studies have described factors associated with the achievement of sustained remission among patients with rheumatoid arthritis.


Rheumatology 2018; doi:10.1093/rheumatology/key202
Arthritis Res Ther 2018; 20: 165

15-08-2018 | Rheumatology | News | Article

Further evidence for the benefits of febuxostat in gout patients with renal impairment

Results of a phase III trial indicate that both the immediate and extended release formulations of febuxostat reduce serum uric acid levels in patients with gout, including those with impaired renal function.


Arthritis Rheumatol 2018; doi:10.1002/art.40685

13-08-2018 | Rheumatology | News

News in brief

Integrated dermatology–rheumatology clinic may improve PsA management

Collaboration between rheumatologists and dermatologists in a combined clinic may help improve outcomes for patients with psoriatic arthritis, study results suggest.

09-08-2018 | Rheumatology | News | Article

Early disease activity may predict methotrexate response, radiographic progression in RA patients

Results of a post-hoc analysis suggest that high early disease activity is associated with poor response to methotrexate and the occurrence of radiographic progression among patients with rheumatoid arthritis.


Ann Rheum Dis 2018; doi:10.1136/annrheumdis-2018-213502

09-08-2018 | Rheumatology | News | Article

News in brief

Equivalence of PF-06438179/GP1111 and infliximab demonstrated

Results of a phase III trial indicate that the infliximab biosimilar PF-06438179/GP1111 has similar efficacy, safety, and immunogenicity profiles to its reference product.

08-08-2018 | Rheumatology | News | Article

Editor's pick

Early signs of cardiac impairment detected in patients with new-onset SLE

Patients with newly diagnosed systemic lupus erythematosus may experience changes to the cardiac extracellular matrix that are indicative of subclinical cardiac impairment, researchers report.


Arthritis Rheumatol 2018; doi:10.1002/art.40671

07-08-2018 | Rheumatology | News | Article

Disease activity linked to osteoporotic fracture risk in RA patients

Patients with rheumatoid arthritis who have high cumulative disease activity and functional disability have an elevated 10-year risk for osteoporotic fracture, researchers report.


Clin Rheumatol 2018; doi:10.1007/s10067-018-4238-4

06-08-2018 | Rheumatology | News | Article

Rituximab may improve lung, skin manifestations of SSc

Results of an open-label randomized trial suggest that rituximab may be an appropriate alternative to cyclophosphamide for treating lung and skin disease associated with systemic sclerosis.


Rheumatology 2018; doi:10.1093/rheumatology/key213

03-08-2018 | Rheumatology | News

News in brief

Oral microbiome imbalance reported in Sjögren’s syndrome patients

Study results suggest that patients with primary Sjögren’s syndrome, and those with similar symptoms, may experience dysbiosis of the buccal mucosa microbiome.

03-08-2018 | Rheumatology | News | Article

Phase II results support further investigation of baricitinib for SLE

Phase II trial results published in The Lancet suggest that adding the Janus kinase 1 and 2 inhibitor baricitinib to standard care may be beneficial for patients with systemic lupus erythematosus.


Lancet 2018; 392: 190–192, 222–231

03-08-2018 | Rheumatology | News | Article

Secukinumab may reduce synovial inflammation in PsA patients

Treatment with the interleukin-17A inhibitor secukinumab is associated with a reduction in synovial inflammation among patients with psoriatic arthritis, results of the PSARTROS study suggest.


Arthritis Res Ther 2018; 20: 153

02-08-2018 | Rheumatology | News | Article

Support for early initiation of biologics in patients with severe JIA

Study results indicate that patients with severe juvenile idiopathic arthritis who start biologic DMARDs within 2 years of symptom onset have better long-term outcomes than those who begin treatment later.


Arthritis Care Res 2018; doi:10.1002/acr.23709

31-07-2018 | Rheumatology | News | Article

Editor's pick

'Dismal' rates of osteoporosis treatment initiation after hip fracture

The proportion of patients initiating osteoporosis medication following hip fracture has declined in recent years, despite treatment reducing subsequent fracture risk, analysis of a US medical claims database suggests.


JAMA Network Open 2018; 1: e180826, e180844

30-07-2018 | Rheumatology | News | Article

Early joint, metabolic complications occur in younger patients with gout

Patients who develop gout before the age of 40 years may experience similar metabolic comorbidities and joint complications as their counterparts with later-onset disease, researchers report.


Arthritis Care Res 2018; doi:10.1002/acr.23706

27-07-2018 | Rheumatology | News | Article

Model developed to predict methotrexate nonresponse in RA patients

Researchers have a developed a model including clinical and psychosocial factors to predict which patients with rheumatoid arthritis are unlikely to respond to methotrexate treatment.


Arthritis Res Ther 2018; 20: 147

27-07-2018 | Rheumatology | News | Article

News in brief

Depression linked to increased RA risk

Study findings suggest that major depressive disorder could be a risk factor for the development of rheumatoid arthritis.

26-07-2018 | Rheumatology | News | Article

Gout may increase atrial fibrillation risk in older people

Having gout is associated with an increased risk for atrial fibrillation among people aged 65 years and older, study results suggest.


RMD Open 2018; 4: e000712

25-07-2018 | Rheumatology | News | Article

Suboptimal diabetes screening in RA patients

Adherence to diabetes screening guidelines is suboptimal among patients with rheumatoid arthritis, Canadian study results suggest.


J Rheumatol 2018; doi:10.3899/jrheum.170973

24-07-2018 | Rheumatology | News | Article

News in brief

Radiation therapy unlikely to be beneficial in hand OA patients

A randomized controlled trial demonstrates no beneficial effect of low-dose radiation therapy for patients with hand osteoarthritis.

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