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Rheumatology

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07-12-2021 | Rheumatology | News | Article

Subclinical synovitis precedes inflammatory arthritis in anti-CCP2+ at-risk people

The majority of people with anti-CCP2 antibodies and musculoskeletal symptoms without clinical synovitis have a period of subclinical synovitis that precedes inflammatory arthritis, research shows.

06-12-2021 | Rheumatology | News | Article

Abatacept may be beneficial for some patients with IgG4-related disease

Findings from a phase 2 proof-of-concept study suggest that abatacept may warrant further investigation as a treatment option for certain subsets of people with IgG4-related disease.

03-12-2021 | Rheumatology | News | Article

Targeting pain should be a priority in systemic sclerosis

Pain affects almost nine in every 10 people with systemic sclerosis, with multiple disease-related factors potentially contributing to pain intensity, researchers report.

02-12-2021 | Rheumatology | News | Article

COVID-19: Meta-analysis suggests increased infection, mortality risk in people with RMDs

A meta-analysis carried out by the COVID-19 Global Rheumatology Alliance suggests that people with rheumatic and musculoskeletal diseases have a higher risk for SARS-CoV-2 infection and mortality than the general population.

30-11-2021 | Rheumatology | News | Article

Study highlights ‘critical importance’ of full COVID-19 vaccination in RMD patients

People with rheumatic and musculoskeletal diseases who experience breakthrough SARS-CoV-2 infection after vaccination have lower rates of poor COVID-19 outcomes than their unvaccinated counterparts, researchers report.

30-11-2021 | Rheumatology | News | Article

B-cell levels may govern success of COVID-19 vaccine booster in rituximab-treated patients

Delaying the third dose of vaccines against SARS-CoV-2 until B-cell repopulation may warrant investigation as a strategy to improve response rates among rituximab-treated patients, suggest findings from a small study.

29-11-2021 | Rheumatology | Highlight | Article

​​​​​​​Telehealth diet, exercise program improves pain, function in knee osteoarthritis

Overweight or obese people with knee osteoarthritis may benefit from a diet- and exercise-focused telehealth intervention, which researchers have shown can improve pain and function over 6 months.

26-11-2021 | Rheumatology | News | Article

RESTORE trial suggests no benefit of platelet-rich plasma injections for knee OA

Intra-articular injections of platelet-rich plasma do not reduce knee pain or disease progression for people with symptomatic mild-to-moderate radiographic medial knee osteoarthritis, suggest findings from a randomized controlled trial.

25-11-2021 | Rheumatology | News | Article

SLE impacts survival after kidney transplant

A retrospective cohort study shows that patients with systemic lupus erythematosus have similar kidney failure outcomes to non-SLE patients, but a higher risk for death after transplantation.

24-11-2021 | Rheumatology | News | Article

Bisphosphonates ‘likely to be beneficial’ for most older women with osteoporosis

Findings from a meta-analysis suggest that bisphosphonate therapy for osteoporosis is most likely to benefit postmenopausal women who have a life expectancy of more than 12 months.

23-11-2021 | Rheumatology | News | Article

Severe hypersensitivity to IL-1, IL-6 inhibitors linked to HLA-DRB1*15

Human leucocyte antigen-DRB1*15 haplotypes are strongly associated with delayed drug reaction with eosinophilia and systemic symptoms in people receiving IL-1 or IL-6 inhibitors for Still’s disease, research suggests.

22-11-2021 | Rheumatology | News | Article

Swollen joints better proxy for synovitis than tender joints in early PsA

Swollen joints are more likely to be associated with ultrasound-confirmed synovitis than tender joints among DMARD-naïve individuals with early psoriatic arthritis, research suggests.

19-11-2021 | Rheumatology | News | Article

Avacopan: EMA recommends approval for ANCA-associated vasculitis

Click through for details on this announcement

18-11-2021 | Rheumatology | News | Article

Excess mortality gap closing, but not for all rheumatic diseases

Individuals with rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis have almost comparable survival rates to those of the general population, Greek study findings indicate.

16-11-2021 | Rheumatology | News | Article

Predictors for PsA in patients with psoriasis identified

Musculoskeletal inflammation and damage is one of several factors that could help predict psoriatic arthritis development among patients with psoriasis, suggest results of a meta-analysis and systematic review.

12-11-2021 | Rheumatology | News | Article

Telemedicine feasible for delivery of SLE follow-up care

Telemedicine might be equally effective to standard in-person follow-up for maintaining disease control in systemic lupus erythematosus patients in the short term, with good levels of patient satisfaction, suggests a 6-month randomized controlled trial.

11-11-2021 | Rheumatology | News | Article

Adherence to a treat-to-target approach in RA not hindered by virtual vs face-to-face visits

A learning collaborative has improved adherence to a treat-to-target approach for patients with rheumatoid arthritis irrespective of whether patients are seen virtually or face to face, show findings from an analysis of 18 US clinics.

11-11-2021 | Rheumatology | News | Article

Real-world study suggests no elevated CV risk with tofacitinib in overall RA population

Tofacitinib is not associated with a higher risk for cardiovascular outcomes than TNF inhibitors in the overall population of people with rheumatoid arthritis, suggest findings from a US database study.

10-11-2021 | Rheumatology | News | Article

High BMI may adversely affect PsA treatment response

Response to treatment for psoriatic arthritis may be impaired for people with obesity, particularly if they are starting a TNF inhibitor, research suggests.

10-11-2021 | Rheumatology | News | Article

Increased risk for breakthrough COVID-19 infection in vaccinated patients with AIRDs

Patients with autoimmune or inflammatory rheumatic diseases may be at increased risk for breakthrough SARS-CoV-2 infection following vaccination, suggests research from two separate cohorts.

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