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20-05-2016 | Diabetes | News | Article

Melatonin signalling may contribute to Type 2 diabetes

Researchers have discovered how a common variant of the melatonin receptor 1b burdens carriers with an increased risk of developing Type 2 diabetes.

29-03-2015 | Paediatrics | Article

CVD risk assessment still important in severely obese adolescents

Researchers report a dose–response relationship between body mass index and cardiovascular risk even in severely obese adolescents, making its assessment important to limit further disease progression.

29-10-2014 | Paediatrics | Article

Obesity genes promote all-round increases in postnatal growth

Genetic variants that increase susceptibility to obesity are associated with increased gains in lean mass, as well as fat mass, during early childhood, meta-analysis findings indicate.

04-09-2014 | Metabolism | Article

Intensive glycaemic control shows ischaemic heart disease benefit

Intensive glucose lowering may significantly reduce the risk of ischaemic heart disease in at-risk middle-aged people with Type 2 diabetes, a post-hoc analysis of the ACCORD trial suggests.

14-08-2014 | Endocrinology | Article

Diet reduces inflammatory markers in ‘real world’ Type 2 diabetes

Encouraging patients newly diagnosed with Type 2 diabetes to diet or to diet and increase their physical activity reduces markers of inflammation and their cardiovascular risk compared with usual care, real-world study findings show.

07-08-2014 | Endocrinology | Article

Inadequate management common in young-onset Type 2 diabetes

Patients with young-onset Type 2 diabetes have worse metabolic control than those with late-onset disease, but they are less likely to receive organ-protective drugs, show data from the Joint Asia Diabetes Evaluation cohort.

31-07-2014 | Metabolism | Article

Salt poses cardiovascular risk in diabetic patients

A diet high in salt increases the risk of cardiovascular disease in patients with Type 2 diabetes, show data from the Japan Diabetes Complications Study.

30-07-2014 | Endocrinology | Article

Thyroxine may overcome mutated thyroid hormone receptor effects

Patients with a mutation in the thyroid hormone receptor α gene that affects both the thyroid hormone receptor α1 and α2 protein variants have similar characteristics to patients with mutations affecting only the α1 variant, report researchers.

30-07-2014 | Endocrinology | Article

Genetic candidates for menarche expanded

A meta-analysis of genome-wide association studies, published in Nature, reveals a large number of genetic variants that may contribute to the age at which girls experience menarche.

30-07-2014 | Endocrinology | Article

Hypertension caution in infants treated for congenital adrenal hyperplasia

High doses of fludrocortisone in the absence of salt supplements can provoke hypertension in infants with congenital adrenal hyperplasia, research shows.

03-07-2014 | Endocrinology | Article

Insulin pumps better than injections for glycaemic control in Type 2 diabetes

Patients with Type 2 diabetes achieve better glycaemic control with insulin pumps than multiple insulin injections, show the findings of the OpT2mise randomised trial.

29-06-2014 | Metabolism | Article

Causal role proposed for vitamin D in blood pressure

The results of a mendelian randomisation analysis suggest a causal link between low levels of vitamin D and increased blood pressure.

29-06-2014 | Endocrinology | Article

Metabolic syndrome components may influence LUTS/BPH

Abdominal aortic calcification and visceral fat obesity each seem to influence lower urinary tract symptoms in men with benign prostatic hyperplasia, study findings suggest.

26-06-2014 | Endocrinology | Article

Vitamin D may not ward off Type 2 diabetes

Vitamin D supplementation is unlikely to improve glycaemic measures in people with prediabetes, show the findings of a randomised trial.

12-06-2014 | Endocrinology | Article

Childhood oestrogen may normalise thelarche in Turner syndrome

Treating girls with Turner syndrome with low-dose oestrogen from childhood results in earlier thelarche and a slower tempo of puberty, research shows.

29-01-2014 | Endocrinology | Article

Psychiatrists urged to monitor metabolic changes in psychosis patients

Japanese psychiatrists are largely aware of the metabolic abnormalities that may arise from antipsychotic treatment, but most do not monitor their patients sufficiently, research shows.

19-01-2014 | Metabolism | Article

Home blood pressure best guide to metabolic risk

Home blood pressure is a good guide to which patients are likely to have the metabolic syndrome, say researchers.

15-12-2013 | Metabolism | Article

Low vitamin D a consequence not a cause of ill health

Low vitamin D status is a marker of ill health rather than an underlying cause of disease, say the authors of a systematic review published in The Lancet Diabetes and Endocrinology.

20-11-2013 | Endocrinology | Article

Type 2 diabetes cytokine elevation places teeth at risk

Scientists have detected significant differences in the cytokine and chemokine make up of gingival crevicular fluid taken from chronic periodontitis patients with uncontrolled Type 2 diabetes and those without.

14-11-2013 | Endocrinology | Article

Diabetic kidney disease BEACON extinguished

The BEACON trial of the synthetic triterpenoid bardoxolone methyl was halted prematurely due to safety concerns, shows research published in the

New England Journal of Medicine