Depression

A collaborative care intervention delivered at urban diabetes clinics improves depressive symptoms and cardiometabolic outcomes among people with comorbid diabetes and depression in India, shows the INDEPENDENT trial.

A telephone-delivered, collaborative goal-setting intervention can significantly reduce depressive symptoms relative to usual care in people with uncontrolled diabetes and clinically significant depression, research shows.

Anxiety and depressive symptoms are associated with pain and disability but not active joint count or biomarkers of inflammation in adolescents with juvenile idiopathic arthritis, researchers report.

Depressive symptoms are common in adolescents with juvenile idiopathic arthritis and could predict future pain and disability, suggests an analysis of the Childhood Arthritis Prospective Study.

Use of a depression treatment program does not improve survival in patients with cancer and comorbid major depression, even though it was highly effective in reducing depressive symptoms, UK researchers report.

Cancer survivors are twice as likely as the general US population to report use of medication for anxiety and depression.

Patients with bipolar disorder regulate their emotions differently from those with major depressive disorder in both depressed and remitted states, a study shows.

Researchers have identified seven clinical features that could help distinguish patients with bipolar disorder from those with major depressive disorder.

Considering genetic variants in combination with early partial improvement could be useful for predicting antidepressant outcome, say researchers.

An online cognitive behavioural therapy programme may help patients with multiple sclerosis who are experiencing depression, research suggests.

Depressive, anxiety and behavioural disorders may be important preceding clinical features in the onset of bipolar disorder, with the potential for targeted preventive care of at-risk individuals, study findings suggest.

Patients with chronic depression can be differentiated from those with episodic depression according to their levels of cognitive–behavioural and emotional avoidance , study findings suggest.

Patients with major depressive disorder or bipolar disorder frequently report chronic pain at multiple sites, research shows.

Poor sleep increases women’s risk for depression by reducing their experience of positive affect in daily life, thereby leading to increased negative reactivity, Dutch researchers believe.

Older men with depression have more frequent and longer hospital stays than those without depressive symptoms, a study shows.

Recurrent brief depression is a valid diagnostic category that can be separated from bipolar II disorder, cyclothymia, and recurrent major depression, study findings indicate.

The feeling of social rejection in patients with depression appears to be associated with physical pain, suggesting that the two characteristics share common neurobiologic circuits, say researchers.

Individuals diagnosed with depression appear to have significantly lower heart rate variability than other people, say Dutch investigators in findings that suggest the association may be due to the effect of antidepressants.

Women with variant forms of the serotonin transporter gene may be particularly vulnerable to depressive symptoms after childbirth, research shows.

While major depression patients starting treatment will spend three quarters of the next decade in euthymia, the remaining quarter will be spent in subthreshold or threshold depression, Japanese study findings indicate.