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Paediatrics

Latest articles

13-01-2022 | Paediatrics | News | Article

Novel loci affect asthma treatment response in children of African descent

Researchers identify novel loci that may contribute to the success of asthma treatment in children of African descent, but find these differ between adolescents and younger children.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

16-12-2021 | Paediatrics | News | Article

Encouraging interim results for Hurler syndrome gene therapy

Altering and reintroducing the haematopoietic stem and progenitor cells of children with Hurler syndrome results in “extensive” correction of metabolic abnormalities, report researchers.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.


06-12-2021 | Oncology | News | Article

High prevalence of multifocal disease highlighted for paediatric papillary thyroid carcinoma

Research points to a high prevalence of multifocal disease in children with papillary thyroid carcinoma, with age and tumour stage possible risk factors for this diagnosis.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

‘No clear benefit’ for morning vs evening 21-OHD high-dose hydrocortisone timing

Levo-thyroxine dose may need more initial adjustment with solution than pills in congenital hypothyroidism

25-11-2021 | Paediatrics | News | Article

Significant and sustained phase 2 results for maralixibat in Alagille syndrome

The bile acid transport inhibitor maralixibat, given at a higher dose than previously tested, may significantly improve cholestasis in children with Alagille syndrome, shows the phase 2 ICONIC trial.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

04-11-2021 | Paediatrics | News | Article

Intranasal oxytocin fails to improve social functioning of autistic children

Intranasal oxytocin therapy did not improve the social or cognitive functioning of children and adolescents with autism in a randomised trial published in The New England Journal of Medicine.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

03-11-2021 | Diabetes | News | Article

Glycemic, life quality benefits of hybrid closed loop shown in young people

Hybrid closed-loop therapy significantly improves glycemic control and quality of life relative to continuous subcutaneous insulin infusion or multiple daily insulin injections in children and adolescents with type 1 diabetes, research shows.

rhGH treatment has positive growth, body composition effects in Kabuki Syndrome

Rare GNAS mutations may underpin severe obesity even in absence of pseudohypoparathyroidism

21-10-2021 | Oncology | News | Article

Hearing loss protection recommendations made for paediatric CNS, head and neck cancer patients

The risk of high-frequency hearing loss in children undergoing cancer treatment to the central nervous system or the head and neck could be reduced by minimising doses of radiation to the cochlea and limiting cumulative doses of cisplatin or carboplatin, Canadian researchers say.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

IGF-I reference curves show healthy infant growth characteristics

Macimorelin shows promise for GHD diagnosis in children

Negative pituitary MRI influences remission, not recurrence of paediatric Cushing’s disease

28-09-2021 | Diabetes | News | Article

Poor hypoglycemia awareness ‘highly prevalent’ in children, young people with type 1 diabetes

Impaired hypoglycemia awareness is present in a substantial proportion of children and young people with type 1 diabetes and is associated with an increased risk for severe hypoglycemia, suggests research presented at the virtual 57th EASD Annual Meeting.

08-09-2021 | Diabetes | News | Article

Linear insulin-to-carbohydrate ratio may not fit all meal requirements

Using a linear insulin to carbohydrate ratio to determine breakfast insulin requirements leads to significant differences in time in glycemic range and hypoglycemia rates when meal carbohydrate quantities vary, shows a study in children and young adults.

Novel ‘BDV syndrome’ has considerable clinical overlap with PWS

Harmonised BMD surveillance guidance for young cancer survivors released

Genetic testing can contribute to clinical diagnosis of delayed puberty

Long-acting growth hormone prodrug ‘superior’ to daily somatropin