Skip to main content
main-content

The independent medical news service

Motor neuron diseases

20-12-2018 | Motor neuron diseases | News | Article

Cannabinoid spray shows anti-spasticity efficacy in motor neuron disease

The oromucosal cannabinoid spray nabiximols has had a positive effect on spasticity symptoms in patients with motor neuron disease in a proof-of-concept trial.

11-04-2016 | Neurology | News | Article

Prognostic markers expanded for AD, ALS

Two studies expand the range of putative prognostic markers for neurological disease, with creatinine kinase found to be prognostic in amyotrophic lateral sclerosis and neurogranin offering diagnostic and prognostic potential in Alzheimer’s disease.

29-02-2016 | Motor neuron diseases | News | Article

Cardiac drug combats muscle cramps in ALS

A phase II study shows that the sodium channel blocker mexiletine has no specific safety concerns in patients with amyotrophic lateral sclerosis and, moreover, markedly reduces muscle cramps.

17-12-2015 | Motor neuron diseases | News | Article

Pauses and reversals ‘not uncommon’ in ALS progression

Patients with amyotrophic lateral sclerosis often have periods of stable disease, with some even experiencing brief improvements, shows analysis of the PRO-ACT database.

09-10-2015 | Motor neuron diseases | News | Article

Role for endogenous retrovirus proposed in ALS pathogenesis

Expression of the human endogenous retrovirus-K is upregulated in some patients with sporadic amyotrophic lateral sclerosis and causes degeneration of motor neurons when overexpressed in mice, research shows.

09-09-2015 | Motor neuron diseases | News | Article

Cortical hyperexcitability has a driving role in ALS

Cortical hyperexcitability is an intrinsic feature of amyotrophic lateral sclerosis symptoms in patients carrying the chromosome 9 open reading frame 72 gene hexanucleotide repeat expansion, show study findings.

05-08-2015 | Motor neuron diseases | News | Article

Diaphragmatic pacing ’harmful’ in amyotrophic lateral sclerosis

Diaphragmatic pacing in conjunction with non-invasive ventilation is detrimental to patients with amyotrophic lateral sclerosis and respiratory insufficiency, show findings from a randomised controlled trial.

04-06-2015 | Motor neuron diseases | News | Article

Gastrostomy methods equivalent in amyotrophic lateral sclerosis

The ProGas study results show that three methods of gastrostomy are equally good in terms of complications and survival in patients with amyotrophic lateral sclerosis.

image credits