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14-02-2017 | Multiple sclerosis | News | Article

Alemtuzumab compares favorably with other potent immunotherapies for MS

Researchers suggest that alemtuzumab is comparable to natalizumab for controlling multiple sclerosis activity and superior to fingolimod and interferon beta.

08-02-2017 | Stroke | Highlight | Article

Prolonged ECG monitoring improves post-stroke atrial fibrillation detection

Research suggests that all patients aged 60 years or older who have had a stroke, irrespective of the suspected cause, could benefit from enhanced and prolonged monitoring for atrial fibrillation.

07-02-2017 | Multiple sclerosis | News | Article

Immunosuppression and stem cell transplants achieve sustained MS remission

High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation can induce long-term remission for patients with relapsing–remitting multiple sclerosis, show findings from the HALT-MS trial.

03-02-2017 | Neurodegeneration | News | Article

Mentally stimulating activities in later life may stave off MCI

Regularly engaging in mentally stimulating activities in later life could help reduce the risk of mild cognitive impairment, research suggests.

01-02-2017 | Neurodegeneration | News | Article

No go for ozanezumab treatment in ALS

Ozanezumab has failed to show efficacy for the treatment of amyotrophic lateral sclerosis in a phase II study, making neurite outgrowth inhibitor A potentially redundant as a treatment target.

31-01-2017 | Neurology | News | Article

Pitolisant reduces cataplexy in narcolepsy patients

Pitolisant, a histamine H3 receptor inverse agonist, has shown promise for the treatment of cataplexy in patients with narcolepsy, investigators report.

26-01-2017 | Multiple sclerosis | News | Article

Serious adverse effect with alemtuzumab reported

Researchers have highlighted the occurrence of severely exacerbated central nervous system inflammation in two patients taking alemtuzumab for multiple sclerosis.

26-01-2017 | Neurology | News | Article

Insufficient evidence prevents OSA screening recommendation

The US Preventive Services Task Force has issued an “I” statement regarding screening for obstructive sleep apnea in adults, concluding that the current evidence is insufficient to assess the balance of benefits and harms.

23-01-2017 | Neurology | News | Article

Volume and location key to predicting preterm neonate WM injury outcomes

Predicting adverse motor and cognitive outcomes in preterm neonates with white matter injury requires the mapping of both lesion volume and location, suggests a magnetic resonance imaging study.

18-01-2017 | Neurology | News | Article

Folic acid supplement recommendation for neural tube defects upheld

The US Preventive Services Task Force has reaffirmed its 2009 recommendation that women who are planning or capable of pregnancy should take a daily supplement containing 400 µg to 800 µg of folic acid for the prevention of neural tube defects.

17-01-2017 | Epilepsy | News | Article

Guideline advises on fMRI use for mapping brain function prior to epilepsy surgery

The American Academy of Neurology has recommended the use of functional magnetic resonance imaging as an alternative to the intracarotid amobarbital procedure for presurgical mapping of language and memory function in patients with epilepsy.

13-01-2017 | Stroke | News | Article

Migraine linked to stroke risk after surgery

Surgical patients with a history of migraine are at increased risk for perioperative ischemic stroke and hospital readmission within 30 days, study findings indicate.

13-01-2017 | Cardiology | News | Article

Brain activity could be key in stress–heart disease link

Researchers report in The Lancet that activity of the amygdala – a central component of the brain involved in emotion and stress – could link stress and cardiovascular disease.

12-01-2017 | Oncology | News | Article

OS promise for 177Lu-dotatate in neuroendocrine tumors

A prespecified interim analysis of the NETTER-1 trial suggests that treatment with lutetium-177–dotatate could prolong overall survival relative to high-dose octreotide long-acting repeatable in patients with metastatic midgut neuroendocrine tumors.

12-01-2017 | Stroke | News | Article

No CLEAR functional benefits for alteplase in intraventricular hemorrhage removal

Irrigation with alteplase to remove intraventricular hemorrhage in patients with intracerebral hemorrhage and a routine extraventricular drain does not substantially improve functional outcome, indicate findings from the CLEAR III trial.

05-01-2017 | Neurodegeneration | News | Article

Living close to major roads increases dementia risk

Living close to major roads is associated with an increased risk for dementia, but not for Parkinson’s disease or multiple sclerosis, study findings reported in The Lancet show.

04-01-2017 | Multiple sclerosis | News | Article

Ocrelizumab shows promise in primary progressive and relapsing–remitting MS

Phase 3 trial results have shown the benefits of ocrelizumab for reducing disability progression in patients with primary progressive multiple sclerosis and disease activity in patients with the relapsing–remitting disease subtype.

23-12-2016 | Epilepsy | News | Article

No added benefit with induced hypothermia for convulsive status epilepticus

Induced hypothermia as an adjunct to standard care fails to improve functional outcome after convulsive status epilepticus, HYBERNATUS study findings show.

22-12-2016 | Alzheimer's disease | News | Article

Protein in urine linked to dementia risk

Albuminuria is modestly associated with the risk for dementia, researchers report in findings supporting the view that cognitive decline and renal dysfunction may be linked.

21-12-2016 | Alzheimer's disease | News | Article

Anti-tau vaccine for AD shows ‘exceptional immunogenicity’

A first-in-human clinical trial of an active vaccine targeting pathologic tau protein in patients with Alzheimer’s disease has shown the vaccine elicits a well-tolerated, strong, and specific immune response.

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