Patients with metastatic renal cell carcinoma reported a marked improvement in their health-related quality of life when given sunitinib on a 2 weeks on and 1 week off schedule compared with a 4 weeks on and 2 weeks off regimen, a Japanese study finds.
Australian researchers report that an alternating regimen of sunitinib and everolimus, although feasible and low-risk in patients with advanced renal cell carcinoma, failed to meet the prespecified criteria for use or continued development.
Statin use prior to undergoing nephrectomy is not associated with survival outcomes in patients with localised renal cell carcinoma, research suggests.
Considering genetic variants in combination with early partial improvement could be useful for predicting antidepressant outcome, say researchers.
Subthreshold manic or hypomanic symptoms frequently precede clinical mood episodes in the children of patients with the condition, a study shows.
The course of bipolar illness is rarely chronic but multiple recurrences are common, suggest findings from a 5-year naturalistic study.
A review of almost one million haematopoietic stem cell transplantation procedures has highlighted differences in the availability of the procedure and the use of autologous and allogeneic transplants across the world.
Laboratory recommendations for the detection and measurement of a deep response to chronic myeloid leukaemia treatment have been developed as part of the European Treatment and Outcome Study for CML.
A Spanish study suggests that bosutinib can help improve or maintain response in patients with chronic myeloid leukaemia after treatment failure of three previous tyrosine kinase inhibitors.
A “seminal” imaging study suggests that worsening memory in adults is not necessarily an indicator of β-amyloid deposition.