Dacomitinib, an irreversible, pan-epidermal growth factor receptor tyrosine kinase inhibitor, does not improve outcomes compared with the first-generation EGFR–TKI erlotinib in patients with advanced non-small-cell lung cancer, irrespective of their KRAS mutation status, finds the ARCHER 1009 study.
An interim analysis of the NELSON study reveals the significance of nodule size and volume doubling time for the risk of cancer in patients who have undergone low-dose computed tomography lung cancer screening.
A treatment strategy designed to minimise the effects of accelerated repopulation using hypofractionated radiotherapy with chemotherapy is feasible for patients with stage III non-small-cell lung cancer, according to UK researchers.
Connectivity within the striatum changes as psychotic symptoms improve in patients treated with second-generation antipsychotics, a study shows.
Clinical features that can appear many years ahead of a psychiatric diagnosis may help doctors to predict whether patients will develop bipolar disorder or unipolar depression, say researchers.
Low-dose computed tomography screening for lung cancer has high specificity and high sensitivity, with just a small number of interval cancers, finds an interim analysis of the NELSON trial.
Treating non-small-cell lung cancer patients with chemotherapy customised according to expression of BRCA1 and receptor-associated protein 80 does not improve progression-free survival compared with nonselected, cisplatin-based chemotherapy, show study findings.
Plasma levels of lithium above the advised range are associated with a transient reduction in kidney function, research shows.
The positive effects of omega-3 supplementation seen in patients at high risk of psychosis in a previous randomised, controlled trial may be sustained, the investigators reported at the International Early Psychosis Conference in Tokyo, Japan.
Women who have never smoked but are exposed to smoking in the home for more than 30 years are at an increased risk of developing lung cancer compared with women without this passive smoking exposure, suggest researchers.