The latest news on the prevention, detection, diagnosis, and prognosis of cancer, and treatment modalities including chemotherapy, surgery, radiotherapy, and hormone therapy.
General oncology
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24 November 2014
Dacomitinib, an irreversible, pan-epidermal growth factor receptor tyrosine kinase inhibitor, does not improve outcomes compared with the first-generation EGFR–TKI erlotinib in patients with advanced non-small-cell lung cancer, irrespective of their KRAS mutation status, finds the ARCHER 1009 study.
24 November 2014
An interim analysis of the NELSON study reveals the significance of nodule size and volume doubling time for the risk of cancer in patients who have undergone low-dose computed tomography lung cancer screening.
21 November 2014
A treatment strategy designed to minimise the effects of accelerated repopulation using hypofractionated radiotherapy with chemotherapy is feasible for patients with stage III non-small-cell lung cancer, according to UK researchers.
19 November 2014
Low-dose computed tomography screening for lung cancer has high specificity and high sensitivity, with just a small number of interval cancers, finds an interim analysis of the NELSON trial.
19 November 2014
Treating non-small-cell lung cancer patients with chemotherapy customised according to expression of BRCA1 and receptor-associated protein 80 does not improve progression-free survival compared with nonselected, cisplatin-based chemotherapy, show study findings.
18 November 2014
Women who have never smoked but are exposed to smoking in the home for more than 30 years are at an increased risk of developing lung cancer compared with women without this passive smoking exposure, suggest researchers.
18 November 2014
A pharmacokinetic–pharmacodynamic model shows that diastolic blood pressure rises with increasing doses of axitinib in patients with metastatic renal cell carcinoma, US researchers report, although this relationship is not linear.
18 November 2014
Statin use at the time of surgery is associated with improved overall survival and disease-specific survival in patients with renal cell carcinoma of any stage, US researchers report.
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